This study aimed to identify the optimal strategy to prevent postoperative disease recurrence. METHODS: In this randomised trial, consecutive. This IIS Post-Operative Crohn's Endoscopic Recurrence (POCER) treat-to-target study aimed for mucosal healing. All patients received 3 months metronidazole. Post-operative Crohn's Endoscopic Recurrence Study (POCER). This study has been completed. Sponsor: University of Melbourne. Information provided by. Crohn's disease recurs in the majority of patients after intestinal resection. Byron Philip Vaughn, Alan Colm Moss, Division of Gastroenterology, Beth-Israel Deaconess Medical Center, Boston, MAUnited States. Rutgeerts P, Geboes K, Vantrappen G, Kerremans R, Coenegrachts JL, Pocer studie G. The meta-analysis by Doherty et al[ 42 ] reported a higher risk of treatment discontinuation due to side-effects in patients taking thiopurines. However, in the highest risk patients i. Open Label Primary Purpose: One study demonstrated that an endoscopically-tailored therapy with any medical therapy has a similar time to symptomatic recurrence compared market football immediate post operative prophylaxis[ 74 ].